New Study: The Cellular Energy Sensor, AMPK - Switching it on for Training Adaptation

by Dr Dan Plews

As we have discussed in several previous blogs, and in our courses, adaptations to endurance training are produced through activation of cellular signalling pathways in response to individual training sessions, with these cellular signalling pathways activated through detection of the physiological stresses generated through exercise. In this blog, we are going to focus on one of the most well-known proteins in the adaptive signalling cascade, the cellular energy sensor AMPK.

AMPK, or to give its full name, 5’adenosine monophosphate-activated protein kinase, is an important protein in the detection of the cellular energy stresses generated during endurance exercise (1). Specifically, AMPK within the muscle is activated by the metabolic stresses generated by exercise, and subsequently activates signalling pathways associated with endurance training adaptation (2). This pathway makes a lot of sense; if our muscle is stressed by exercise, we detect it and then...

Continue Reading...

How to Taper for Triathlon

endurance training ldt102 Sep 23, 2021

We all know that the pre-competition taper is one of the fundamental components of the build-up to an endurance event. In this short blog, we will briefly cover some of the science behind the purpose of, and best practices in, tapering. We cover the science and practice of the pre-competition taper in much more detail in LDT102, our course on training programme fundamentals.

 Why do we need to taper?

In order to optimise your taper, it is important to first understand what a taper is trying to achieve. Tapering has been defined as the deliberate reduction in training load in the days prior to competition (4), the purpose of which is to provide the athlete with sufficient rest and recovery to perform at their best, but without reversing the adaptations gained through training (6). Tapering is therefore a balancing act between providing rest and recovery and preventing detraining.

Crucially, tapering has been shown across a number of investigations to be beneficial to endurance...

Continue Reading...


Get the latest Brew Up newsletter from Endure IQ's founder, Dr. Dan Plews.